Color Holographic Visualization of an Abnormal Retina: A Training Guide

Abstract:
“Holographic projection is one of the efficient tools to provide accurate three-dimensional (3D) representation of the medical data. Here, the aim of the current study is the construction of color holographic projection system to visualize an abnormal retina. The structures of the retina (blood vessels, optic disk, and ocular toxoplasmosis) are segmented using an in-house developed matlab code. The computer-generated holograms (CGHs) of the segmented structures are calculated using iterative Fourier transform algorithm (IFTA) and projected using a phase-only spatial light modulator (SLM). During the calculation process, a speckle noise reduction algorithm was applied to decrease the speckle noise of the optically reconstructed images. This is achieved by calculating an extended CGH and dividing it into a set of 16 equal holograms. The temporal-multiplexing of the 16 hologram yields a speckle-free reconstructed image. High quality Colored optical reconstruction images of an abnormal retinal structure were obtained using the proposed holographic projection system. Therefore, the proposed system can be used in corporation with the fundus photography as a significant tool for improving diagnosis and treatment of ocular toxoplasmosis.”