Holographic data storage (HDS) has emerged as a promising technology for high-capacity data storage. In this study, we propose a novel approach to enhance the storage density in HDS through a multiplexing perfect optical vortex (POV) hologram. By utilizing the orthogonality property of POV, different POV-recording holograms can be multiplexed to store multiple data pages within the single hologram. Compared with the conventional optical vortex, the better storage density of POV through proof-of-principle experiments is demonstrated. For the POV-multiplexing hologram of six data pages, each one can be reconstructed successfully. In addition, we investigate the impact of axicon periods and multiplexing numbers on the storage performance. Our results reveal that an appropriate selection of axicon periods and multiplexing numbers is crucial to balance storage density and bit error rate (BER). The proposed multiplexing approach offers a valuable solution for achieving high-density and secure holographic data storage systems.