Author(s):

Houkai Chen and Xiaojing Wu and Yuquan Zhang and Yong Yang and Changjun Min and Siwei Zhu and Xiaocong Yuan and Qiaoliang Bao and Jing Bu

Abstract:

“Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.”

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