Singular Warped Beams Controlled by Tangent Phase Modulation

Author(s):

Funes, Gustavo; Peters, Eduardo & Anguita, Jaime

Abstract:

“We analyze the effect of spatial phase modulation using non-linear functions applied to singular warped beams to control their topological states and intensity distribution. Such beams are candidates for optical trapping and particle manipulation for their controllable pattern of intensities and singularities. We first simulate several kinds of warped beams to analyze their intensity profiles and propagation characteristics. Secondly, we experimentally validate the simulations and investigate the far-field profiles. By calculating the intensity gradients, we describe how these beams are qualified candidates for optical manipulation and trapping.”

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Publication: Photonics
Issue/Year: Photonics, Volume 8; Number 8; Pages 343; 2021
DOI: 10.3390/photonics8080343

Manipulating aqueous droplets by light-induced virtual electrodes

Author(s):

Zamboni, Riccardo; Imbrock, Jörg & Denz, Cornelia

Abstract:

“The precise spatio-temporal manipulation of droplets is fundamental for many lab-on-a-chip systems with applications in biology, healthcare and chemistry. Different approaches have been investigated, including thermal, chemical and electrical methodologies. Among this latter, electrophoresis (EP) and dielectrophoresis (DEP) play a key role, since they are highly compatible with microfluidic systems and provide sufficiently strong forces to control up to microliter volume aqueous droplets. However, EP and DEP techniques typically require the presence of metallic electrodes to create the desired electric fields, making these approaches less flexible and efficient than those exploiting pure optical techniques. Iron-doped lithium niobate (LiNbO3:Fe) allows for the generation of strong electric field modulation due to an inhomogenous illumination, thanks to its photovoltaic properties. These photoinduced fields interact as EP and DEP forces with microdroplets, while guaranteeing the flexibility provided by optical field-based modulation. Indeed, the combination with well-known techniques to control and modulate light fields can be exploited to generate virtual electrodes on the material, achieving reliable as well as flexible devices for water droplets control. In our approach, the photoinduced fields generated by the complex illumination of LiNbO3:Fe are exploited to control motion and trajectory of water droplets inside microfluidic channel. Moreover, the crystal is integrated in standard droplet microfluidic polymeric device, substituting the usual glass substrate and, thus without hindering the portability. This feature combined with the control of positions of aqueous droplets represents a key tool for several applications of customized lab-on-a-chip systems, highlighting the capabilities of LinbO3:Fe-based virtual electrodes.”

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Publication: SPIE Proceedings
Issue/Year: Proc. SPIE 11798, Optical Trapping and Optical Micromanipulation XVIII, 1179824, 2021
DOI: 10.1117/12.2594165

Optically Manipulated Microtools to Measure Adhesion of the Nanoparticle-Targeting Ligand Glutathione to Brain Endothelial Cells

Author(s):

Tamás Fekete, Mária Mészáros, Zsolt Szegletes, Gaszton Vizsnyiczai, László Zimányi, Mária A. Deli, Szilvia Veszelka*, and Lóránd Kelemen

Abstract:

“Targeting nanoparticles as drug delivery platforms is crucial to facilitate their cellular entry. Docking of nanoparticles by targeting ligands on cell membranes is the first step for the initiation of cellular uptake. As a model system, we studied brain microvascular endothelial cells, which form the anatomical basis of the blood–brain barrier, and the tripeptide glutathione, one of the most effective targeting ligands of nanoparticles to cross the blood–brain barrier. To investigate this initial docking step between glutathione and the membrane of living brain endothelial cells, we applied our recently developed innovative optical method. We present a microtool, with a task-specific geometry used as a probe, actuated by multifocus optical tweezers to characterize the adhesion probability and strength of glutathione-coated surfaces to the cell membrane of endothelial cells. The binding probability of the glutathione-coated surface and the adhesion force between the microtool and cell membrane was measured in a novel arrangement: cells were cultured on a vertical polymer wall and the mechanical forces were generated laterally and at the same time, perpendicularly to the plasma membrane. The adhesion force values were also determined with more conventional atomic force microscopy (AFM) measurements using functionalized colloidal probes. The optical trapping-based method was found to be suitable to measure very low adhesion forces (≤ 20 pN) without a high level of noise, which is characteristic for AFM measurements in this range. The holographic optical tweezers-directed functionalized microtools may help characterize the adhesion step of nanoparticles initiating transcytosis and select ligands to target nanoparticles.”

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Publication: ACS Applied Materials & Interfaces
Issue/Year: ACS Applied Materials & Interfaces, Volume 13; Number 33; Pages 39018–39029; 2021
DOI: 10.1021/acsami.1c08454

Twin curvilinear vortex beams

Author(s):

Wang, Zhuang; Yuan, Zheng; Gao, Yuan; Yan, Wenxiang; Liang, Chunjuan; Ren, Zhi-Cheng; Wang, Xi-Lin; Ding, Jianping & Wang, Hui-Tian

Abstract:

“We report on a novel curvilinear optical vortex beam named twin curvilinear vortex beams (TCVBs) with intensity and phase distribution along a pair of two- or three-dimensional curves, both of which share the same shape and the same topological charge. The TCVBs also possess the character of perfect optical vortex, namely having a size independent of topological charge. We theoretically demonstrate that a TCVB rather than a single-curve vortex beam can be created by the Fourier transform of a cylindrically polarized beam. The behavior of TCVBs generated through our method is investigated by simulation and experiment, including interference experiments for identifying the vortex property of the TCVBs. The TCVBs may find applications in optical tweezers, such as trapping low refractive index particles in the dark region between two curves and driving them moving along the curvilinear trajectory.”

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Publication: Optics Express
Issue/Year: Optics Express, Volume 29; Number 9; Pages 14112; 2021
DOI: 10.1364/oe.423803

Flexible rotation of transverse optical field for 2D self-accelerating beams with a designated trajectory

Author(s):

Li, Zongtao; Cao, Kai; Li, Jiasheng; Tang, Yong; Ding, Xinrui & Yu, Binhai

Abstract:

“Self-accelerating beams have the unusual ability to remain diffraction-free while undergo the transverse shift during the free-space propagation. We theoretically identify that the transverse optical field distribution of 2D self-accelerating beam is determined by the selection of the transverse Cartesian coordinates, when the caustic method is utilized for its trajectory design. Based on the coordinate-rotation method, we experimentally demonstrate a scheme to flexibly manipulate the rotation of transverse optical field for 2D self-accelerating beams under the condition of a designated trajectory. With this scheme, the transverse optical field can be rotated within a range of 90 degrees, especially when the trajectory of 2D self-accelerating beams needs to be maintained for free-space photonic interconnection.”

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Publication: Opto-Electronic Advances
Issue/Year: Opto-Electronic Advances, Volume 4; Number 3; Pages 20002101–20002115; 2021
DOI: 10.29026/oea.2021.200021

Generation of Complex Transverse Energy Flow Distributions with Autofocusing Optical Vortex Beams

Author(s):

Khonina, Svetlana N.; Porfirev, Alexey P.; Ustinov, Andrey V. & Butt, Muhammad Ali

Abstract:

“Optical vortex (OV) beams are widely used for the generation of light fields with transverse energy flow inducing orbital motion of the nano- and microparticles in the transverse plane. Here, we present some new modifications of OV beams with autofocusing properties for shaping complex transverse energy flow distributions varying in space. The angular component of the complex amplitude of these beams is defined by the superpositions of OV beams with different topological charges. The proposed approach provides a convenient method to control the three-dimensional structure of the generated autofocusing OV beams. The control of the transverse distribution of an autofocusing beam provides a wide variety of generated fields with both rotating and periodic properties, which can be used in the field of laser manipulation and laser material processing. Thus, the obtained numerical results predict different types of motion of the trapped particles for the designed OV autofocusing beams. The experimental results agree with modeling results and demonstrate the principal possibility to shape such laser beams using spatial light modulators.”

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Publication: Micromachines
Issue/Year: Micromachines, Volume 12; Number 3; Pages 297; 2021
DOI: 10.3390/mi12030297

Experimental optical trapping of micro-particles with Frozen Waves

Author(s):

Rafael A. B. Suarez and Antonio A. R. Neves and Marcos R. R. Gesualdi and Leonardo A. Ambrosio and Michel Zamboni-Rached

Abstract:

“This work presents the first optical trapping experimental demonstration of micro-particles with Frozen Waves. Frozen Waves are an efficient method to model longitudinally the intensity of non-diffracting beams obtained by superposing co-propagating Bessel beams with the same frequency and order. The experimental setup of a holographic optical tweezers using spatial light modulators has been assembled and optimized. We investigate the optical force distribution acting on micro-particles of two types of Frozen Waves.The results show that it is possible to obtain greater stability for optical trapping using Frozen Waves. The significant enhancement in trapping geometry from this approach shows promising applications for optical tweezers, micro-manipulations over a broad range. ”

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Publication: Optics Letters
Issue/Year: Vol. 45, Issue 9, pp. 2514-2517
DOI: 10.1364/OL.390909

Rapid tilted-plane Gerchberg-Saxton algorithm for holographic optical tweezers

Author(s):

Yanan Cai, Shaohui Yan, Zhaojun Wang, Runze Li, Yansheng Liang, Yuan Zhou, Xing Li, Xianghua Yu, Ming Lei and Baoli Yao

Abstract:

“Benefitting from the development of commercial spatial light modulator (SLM), holographic optical tweezers (HOT) have emerged as a powerful tool for life science, material science and particle physics. The calculation of computer-generated holograms (CGH) for generating multi-focus arrays plays a key role in HOT for trapping of a bunch of particles in parallel. To realize dynamic 3D manipulation, we propose a new tilted-plane GS algorithm for fast generation of multiple foci. The multi-focal spots with a uniformity of 99% can be generated in a tilted plane. The computation time for a CGH with 512512 pixels is less than 0.1 second.
We demonstrated the power of the algorithm by simultaneously trapping and rotating silica beads with a 77 spots array in three dimensions. The presented algorithm is expected as a powerful kernel of HOT.”

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Publication: Optics Express
Issue/Year: Vol. 28, Issue 9, pp. 12729-12739
DOI: 10.1364/OE.389897

Generation of Tunable Fractional Vector Curvilinear Beams With Controllable Phase Distribution

Author(s):

Fengyan Gu, Zhongzheng Gu, Chenliang Chang, Caojin Yuan, Shaotong Feng, Fangjian Xing and Shouping Nie

Abstract:

“An approach to generate the tunable fractional vector curvilinear beams (VCBs) was proposed. The scheme is based on the vector optical field generator (VOFG) system, where the two orthogonal polarized scalar curvilinear beams (SCBs) are generated to be the base vector components, and coaxially superposed by a Ronchi grating. We design a new phase distribution with several loops of 0 to π in order to generate more dark gaps. The phase distribution becomes nonuniform by varying the phase variation rate and the positions of the dark gaps are changed. Using the different parameters of the curves, the fractional VCBs with different shapes are achieved. The two orthogonal polarized SCBs with the opposite topological charges are modulated to perform the beam conversion by a phase-only computer-generated hologram (CGH). Our experimental results comply with the theory and the radial opening of the dark gaps may have some applications for guiding and transporting particles.”

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Publication: IEEE Photonics Journal
Issue/Year: Volume: 11 Issue: 6 (2019)
DOI: 10.1109/JPHOT.2019.2942041

Generation of reconfigurable optical traps for microparticles spatial manipulation through dynamic split lens inspired light structures

Author(s):

Angel Lizana and Haolin Zhang and Alex Turpin and Albert Van Eeckhout and Fabian A. Torres-Ruiz and Asticio Vargas and Claudio Ramirez and Francesc Pi and Juan Campos

Abstract:

“We present an experimental method, based on the use of dynamic split-lens configurations, useful for the trapping and spatial control of microparticles through the photophoretic force. In particular, the concept of split-lens configurations is exploited to experimentally create customized and reconfigurable three-dimensional light structures, in which carbon coated glass microspheres, with sizes in a range of 63–75 μm, can be captured. The generation of light spatial structures is performed by properly addressing phase distributions corresponding to different split-lens configurations onto a spatial light modulator (SLM). The use of an SLM allows a dynamic variation of the light structures geometry just by modifying few control parameters of easy physical interpretation. We provide some examples in video format of particle trapping processes. What is more, we also perform further spatial manipulation, by controlling the spatial position of the particles in the axial direction, demonstrating the generation of reconfigurable three-dimensional photophoretic traps for microscopic manipulation of absorbing
particles.”

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Publication: Scientific Reports
Issue/Year: Scientific Reports volume 8, Article number: 11263 (2018)
DOI: 10.1038/s41598-018-29540-1
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