Relay-projection microscopic telescopy

PLUTO / PLUTO-2 Spatial Light Modulators
Imaging/ Image Processing Microscopy
Published on:
Authors: Wenjun Yi, Shuyue Zhu, Meicheng Fu, Nan Gu, Junli Qi, Siyu Liu, Mengjun Zhu, Ping Wang, Xin Chen, Yi Zhang, Hongyu Zhang, Yao Xu, Junyi Du, Peng Xiong, Zhaohua Dong, Luobing Dong, Qiong Liu and Xiujian Li
Abstract:

The fundamental trade-off between spatial resolution and imaging distance poses a significant challenge for current imaging techniques, such as those used in modern biomedical diagnosis and remote sensing. Here, we introduce a new conceptual method for imaging dynamic amplitude-phase-mixed objects, termed relay-projection microscopic telescopy (rPMT), which fundamentally challenges conventional light collection techniques by employing non-line-of-sight light collection through square-law relay-projection mechanisms. We successfully resolved tiny features measuring 2.76 μm, 22.10 μm, and 35.08 μm for objects positioned at distances of 1019.0 mm, 26.4 m, and 96.0 m, respectively, from single-shot spatial power spectrum images captured on the relay screen; these results demonstrate that the resolution capabilities of rPMT significantly surpass the Abbe diffraction limit of the 25 mm-aperture camera lens at the respective distances, achieving resolution improvement factors of 7.9, 25.4, and 58.2. The rPMT exhibits long-distance, wide-range, high-resolution imaging capabilities that exceed the diffraction limit of the camera lens and the focusing range limit, even when the objects are obscured by a scattering medium. The rPMT enables telescopic imaging from centimeters to beyond hundreds of meters with micrometer-scale resolution using simple devices, including a laser diode, a portable camera, and a diffusely reflecting whiteboard. Unlike contemporary high-resolution imaging techniques, our method does not require labeling reagents, wavefront modulation, synthetic receive aperture, or ptychography scanning, which significantly reduce the complexity of the imaging system and enhance the application practicality. This method holds particular promise for in-vivo label-free dynamic biomedical microscopic imaging diagnosis and remote surveillance of small objects.

Open Access

Publication: Light: Science & Applications
Issue/Year: Light Sci Appl 14, 117 (2025)
DOI: 10.1038/s41377-025-01800-6
Link: https://doi.org/10.1038/s41377-025-01800-6

Related Papers

PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Yangjun Li, Hangyu Zhang, Chenzhe Jiang, Leihong Zhang, and Dawei Zhang

Computational ghost imaging for atmospheric turbulence using model-driven and data-driven deep learning

Applications: Deep Learning / Neuronal Network,Imaging/ Image Processing,Turbid-/ Opaque Media /Multi Scattering
GAEA / GAEA-2 Spatial Light Modulators
Authors:Kyosik Min, Myeong-Ho Choi, and Jae-Hyeung Park

Quality enhancement of computer-generated hologram without contents-dependent optimization by considering aberrations in the optical system

Applications: AR/VR/MR / Holographic Display,Deep Learning / Neuronal Network,Imaging/ Image Processing
GAEA / GAEA-2 Spatial Light Modulators
Authors:Tobias Wilm, Reinhold Fiess, and Ulrich Seger

In-situ automotive camera calibration using holographic resolution targets

Applications: Digital-/ Computer Holography/ CGH,Imaging/ Image Processing,Materials Processing / Optical Fabrication,Misc.: Speckle / Characterization / Metrology
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Carlos Vargas-Castrillón, Alejandro Velez-Zea, and John Fredy Barrera-Ramírez

Intensity equivalence between free-space propagation and a single-lens processor: application to adjustable magnification in hologram reconstruction

Applications: Adaptive Optics / Wavefront Control,Digital-/ Computer Holography/ CGH,Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Adolphe Ndagijimana, Iñigo Ederra and Miguel Heredia Conde

Single-Pixel Compressive Terahertz 3D Imaging

Applications: Complex Modulation,Imaging/ Image Processing
LETO / LETO-3 Spatial Light Modulators
Authors:Binxiong Pan, Baoju Wang, Yue Ni, Qi Zhao, Yuqi Wang, Yuyan Cai, and Qiuqiang Zhan

Sidelobe-free deterministic 3D nanoscopy with λ/33 axial resolution

Applications: Microscopy
LETO / LETO-3 Spatial Light Modulators
Authors:Augusto Arias, Susanna P. Clement, Pablo Artal and Siegfried Wahl

Chromatic imaging properties of myopia control spectacle lenses

Applications: Adaptive Optics / Wavefront Control,Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Yu-Chen Chen, Shi-Xuan Mi, Ya-Ping Tian, Xiao-Bo Hu, Qi-Yao Yuan, Khian-Hooi Chew and Rui-Pin Chen

Adaptive Vectorial Restoration from Dynamic Speckle Patterns Through Biological Scattering Media Based on Deep Learning

Applications: Adaptive Optics / Wavefront Control,Deep Learning / Neuronal Network,Digital-/ Computer Holography/ CGH,Imaging/ Image Processing,Microscopy,Misc.: Speckle / Characterization / Metrology,Phase Measurement / Phase Retrieval,Polarization Generation,Turbid-/ Opaque Media /Multi Scattering
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Allarakha Shikder, Naveen K. Nishchal

Image encryption using arbitrary modes of Hermite-Gaussian beams

Applications: Higher Order Modes / Optical Vortex / OAM,Imaging/ Image Processing,Optical Computing / Quantum Optics
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Jawahar Prabhakar Desai, Vijayakumar Anand and Joseph Rosen

Multiple Incoherent Deconvolutions for Improving the Image Resolution of Diffraction-Limited Imaging Systems

Applications: Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Han Gao, Li Pei, Jianshuai Wang, Zhouyi Hu, Bing Bai, Tigang Ning, Kaihua Hu, and Wenxuan Xu

Enhanced angular misalignment resiliency in multimode fiber imaging leveraging deep learning

Applications: Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Ruisi Wang

Visualization of pure phase objects with optical spatial differentiation operations

Applications: Imaging/ Image Processing,Phase Measurement / Phase Retrieval
LC-R 720 Spatial Light Modulators
Authors:Xuan Liu, Rupak Bhakta, Emily Kryvorutsky and Yuanwei Zhang

Imaging cells and nanoparticles using modulated optically computed phase microscopy

Applications: Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Zhenting Yan, Huiling Huang, Yili Chen, Hanfei Lin, Ebraheem Farea, Xingzhao Hua and Jun Han

Scattering imaging of moving targets based on recurrent neural networks: a fusion of temporal and phase information

Applications: Deep Learning / Neuronal Network,Imaging/ Image Processing,Turbid-/ Opaque Media /Multi Scattering
LC 2002 Spatial Light Modulators
Authors:Jyoti Bikash Mohapatra, Naveen K. Nishchal and Jyothish Monikantan

Object Recognition in Foggy and Hazy Conditions Using Dark Channel Prior-Based Fringe-Adjusted Joint Transform Correlator

Applications: Digital-/ Computer Holography/ CGH,Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Sara Aissati, Tianlun Zou, Sabyasachi Goswami, Len Zheleznyak, Susana Marcos

Visual Quality and Accommodation With Novel Optical Designs for Myopia Control

Applications: Imaging/ Image Processing,Misc.: Speckle / Characterization / Metrology
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:R. Gottschalk, A. Lindinger

Interference patterns of two-photon excited fluorescence by spatial beam shaping

Applications: Adaptive Optics / Wavefront Control,Imaging/ Image Processing,Microscopy
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Jacob Kher-Aldeen, Kobi Cohen, Stav Lotan, Kobi Frischwasser, Bergin Gjonaj, Shai Tsesses & Guy Bartal

Dynamic control and manipulation of near-fields using direct feedback

Applications: Beam Shaping / Beam Steering,Microscopy
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Xu-Zhen Gao, Qing-Lu Li, Tian-Fei Zhao, Ya-Ning Kong, Guo-Dong Tan and Yue Pan

Flexible focal array engineering with a binary array vector optical field

Applications: Beam Shaping / Beam Steering,Higher Order Modes / Optical Vortex / OAM,Imaging/ Image Processing,Optical Trapping /-Tweezers
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Yuxin Lu, Wenjing Zhao, Aiping Zhai, Nuo Liu and Dong Wang

Single-pixel phase imaging via a complex-valued Zernike basis

Applications: Adaptive Optics / Wavefront Control,Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Dongxu Zhou, Hongzhi Zhang, Hongyan Yu, and Guoquan Zhang

High-visibility calculating ghost imaging with self-reconstruction capability and extendible depth-of-field

Applications: Imaging/ Image Processing,Turbid-/ Opaque Media /Multi Scattering
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Jixiang Wang, Xin Xu, Hong Ye, Xin Zhang, and Guohua Shi

Efficient generation of high-contrast Bessel light sheets: a flexible method for improved imaging

Applications: Beam Shaping / Beam Steering,Bessel-/ Airy Beam Generation,Imaging/ Image Processing,Microscopy
LC 2012 PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Jiaosheng Li, Yifei Chen, Tianyun Liu, Bo Wu & Qinnan Zhang

Single-pixel Fresnel incoherent correlation holography compressed imaging using a Trumpet network

Applications: Deep Learning / Neuronal Network,Digital-/ Computer Holography/ CGH,Imaging/ Image Processing
PLUTO / PLUTO-2 Spatial Light Modulators
Authors:Juntao Hu, Wenjun Wei, Xinzhong Li, and Yixian Qian

Generation of polygonal non-diffracting beams via angular spectral phases

Applications: Beam Shaping / Beam Steering,Higher Order Modes / Optical Vortex / OAM,Microscopy